Search this journal:     Advanced search
Posters

Investigation of water sources as reservoirs of Vibrio cholerae in Bepanda, Douala and determination of physico-chemical factors maintaining its endemicity

Akoachere J.-F.K. Tatah, Kwedjeu M.C. Pulcherie, Ndip L. Mande, Njom H. Akum

Onderstepoort J Vet Res; Vol 79, No 2 (2012), 1 page. doi: 10.4102/ojvr.v79i2.484

Submitted: 13 June 2012
Published:  20 June 2012

Abstract

Cholera remains a significant cause of mortality in developing countries. Outbreaks of the disease are associated with poverty, lack of potable water and poor sanitation. The survival and persistence of Vibrio cholerae in water has been shown to depend on physico-chemical factors. We studied water sources in Bepanda, an overcrowded neighbourhood in Douala, Cameroon, with limited access to portable water and very poor sanitary conditions as reservoirs of V. cholerae.

We analysed 318 samples from various sources (well, tap, stream) from February to July 2009 using standard microbiological techniques and characterised isolates serologically using the polyvalent O1/O139 antisera. Susceptibility to antibiotics previously used for cholera treatment in Douala was studied using the disk diffusion method. Physico-chemical factors (temperature, pH and salinity) that could maintain the endemicity of the organism were analysed using standard methods. Eighty-seven (27.4%) samples were contaminated, with high isolation rates being obtained from streams (52.4%) and wells (29.8%). The number of isolates was significantly higher (P < 0.05) in the rainy season (35.5%). We detected 23 (24%) O1 serogroup isolates in streams and wells, whilst 64 (66.6%) were non-O1/non-O139. Temperature and salinity correlated positively with the occurrence of the organisms. All isolates were susceptible to fluoroquinolones but high resistance rates to trimethoprim or sulfamethozaxole and tetracycline were observed.

Vibrio cholerae is endemic in Bepanda with O1 and non-O1/non-O139 serogroups co-existing in the streams and wells hence the possibility of future outbreaks of cholera if sanitation and drinking water quality are not improved. Temperature and salinity are amongst the factors maintaining the endemicity of the organism.


Full Text:  |  HTML  |  EPUB  |  XML  |  PDF (246KB)

Author affiliations

Akoachere J.-F.K. Tatah, Department of Biochemistry and Microbiology, University of Buea, Cameroon
Kwedjeu M.C. Pulcherie, Department of Biochemistry and Microbiology, University of Buea, Cameroon
Ndip L. Mande, Department of Biochemistry and Microbiology, University of Buea, Cameroon
Njom H. Akum, Laboratory for Emerging Infectious Diseases, University of Buea, Cameroon

Metrics

Total abstract views: 690
Total article views: 1917  

Cited-By

1. Assessment of the relationship between bacteriological quality of dug-wells, hygiene behaviour and well characteristics in two cholera endemic localities in Douala, Cameroon
Jane-Francis Tatah Akoachere, Lundi-Anne Omam, Thomas Massalla
BMC Public Health  vol: 13  issue: 1  first page: 692  year: 2013  
doi: 10.1186/1471-2458-13-692

2. Optimal surveillance network design: a value of information model
Matteo Convertino, Yang Liu, Haejin Hwang
Complex Adaptive Systems Modeling  vol: 2  issue: 1  year: 2014  
doi: 10.1186/s40294-014-0006-8

Comments on this article

Before posting your comment, please read our policy.
Post a Comment (Login required)


ISSN: 0030-2465 (print) | ISSN: 2219-0635 (online) Follow us on:

All articles published in this journal are licensed under the Creative Commons Attribution license.

©2015 AOSIS (Pty) Ltd. All rights reserved. No unauthorised duplication allowed.

AOSIS OpenJournals | Perfecting Scholarship Online
Postnet Suite #110, Private Bag X19, Durbanville, South Africa, 7551
Tel: 086 1000 381
Tel: +27 21 975 2602
Fax: 086 5004 974

Please read the privacy statement.